Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis.

Recurrent herpetic keratouveitis following YAG laser peripheral iridotomy.

OBJECTIVE To report recurrent herpetic keratouveitis following YAG laser peripheral iridotomy. METHODS Case report. RESULTS A 64-year-old woman with a history of dendritic keratitis underwent Nd:YAG laser peripheral iridotomy and developed geographic epithelial keratitis with stromal keratouveitis. Culture of a corneal swab grew herpes simplex virus type I. Keratouveitis subsided with acycl...

Efficacy of a recombinant glycoprotein D subunit vaccine on the development of primary and recurrent ocular infection with herpes simplex virus type 1 in mice.

The protective efficacy of a glycoprotein D subunit vaccine (gD2 SB AS4) was evaluated in a mouse model of human recurrent herpetic stromal keratitis (HSK). When administered before primary infection, gD2 SB AS4 protected mice against corneal pathology, mortality, and latency resulting from ocular viral challenge with herpes simplex virus type 1 (HSV-1) McKrae strain. In addition, gD2 SB AS4 si...

[Bilateral herpetic keratouveitis in an immunocompetent patient].

CASE REPORT We report the case of an immunocompetent male who presented with a limbal-adjacent scleritis and interstitial keratitis in the left eye. A few days later a new dendritiform ulcer in his right eye and bilateral progressive worsening with granulomatous uveitis in both eyes were observed. A thorough review of systems revealed positive serum IgM titles for herpes simplex virus. DISCUS...

The fate of experimental corneal grafts in herpetic keratitis and keratouveitis.

G'orneal graft opacification may occur in the course of ocular inflammation' 2 and graft rejection may develop concommitantly or stimulated by the inflammation/' The incidence of immune graft rejections during episodes of iritis or external infections is difficult to document, due to the fact that it is not possible at the present time to separate clinically one process from the other. In our e...

A Diagnostic Multiplex Polymerase Chain Reaction Assay for Ocular Herpetic Infections.